diff --git a/src/Compiler/AbstractIL/il.fs b/src/Compiler/AbstractIL/il.fs
index fecefad1434..0b4c66ef35f 100644
--- a/src/Compiler/AbstractIL/il.fs
+++ b/src/Compiler/AbstractIL/il.fs
@@ -2073,6 +2073,10 @@ type ILMethodDef
 
     member x.IsMustRun = x.ImplAttributes &&& MethodImplAttributes.NoOptimization <> enum 0
 
+    /// Check if method is marked with MethodImplOptions.Async (0x2000)
+    /// This indicates the method uses runtime-async support (.NET 10+)
+    member x.IsAsync = x.ImplAttributes &&& enum<MethodImplAttributes>(0x2000) <> enum 0
+
     member x.WithSpecialName =
         x.With(attributes = (x.Attributes ||| MethodAttributes.SpecialName))
 
@@ -2132,6 +2136,10 @@ type ILMethodDef
     member x.WithRuntime(condition) =
         x.With(implAttributes = (x.ImplAttributes |> conditionalAdd condition MethodImplAttributes.Runtime))
 
+    /// Set the Async flag (MethodImplOptions.Async = 0x2000) for runtime-async support (.NET 10+)
+    member x.WithAsync(condition) =
+        x.With(implAttributes = (x.ImplAttributes |> conditionalAdd condition (enum<MethodImplAttributes>(0x2000))))
+
     [<DebuggerBrowsable(DebuggerBrowsableState.Never)>]
     member x.DebugText = x.ToString()
 
diff --git a/src/Compiler/AbstractIL/il.fsi b/src/Compiler/AbstractIL/il.fsi
index 5e02f4c0c1e..72e3d25790c 100644
--- a/src/Compiler/AbstractIL/il.fsi
+++ b/src/Compiler/AbstractIL/il.fsi
@@ -1134,6 +1134,9 @@ type ILMethodDef =
     /// SafeHandle finalizer must be run.
     member IsMustRun: bool
 
+    /// Indicates method uses runtime-async support (MethodImplOptions.Async = 0x2000, .NET 10+)
+    member IsAsync: bool
+
     /// Functional update of the value
     member internal With:
         ?name: string *
@@ -1179,6 +1182,9 @@ type ILMethodDef =
 
     member internal WithRuntime: bool -> ILMethodDef
 
+    /// Set the Async flag (MethodImplOptions.Async = 0x2000) for runtime-async support (.NET 10+)
+    member internal WithAsync: bool -> ILMethodDef
+
 /// Tables of methods.  Logically equivalent to a list of methods but
 /// the table is kept in a form optimized for looking up methods by
 /// name and arity.
diff --git a/src/Compiler/CodeGen/IlxGen.fs b/src/Compiler/CodeGen/IlxGen.fs
index 5c174ecf9de..ae6a7e616d5 100644
--- a/src/Compiler/CodeGen/IlxGen.fs
+++ b/src/Compiler/CodeGen/IlxGen.fs
@@ -9002,8 +9002,11 @@ and ComputeMethodImplAttribs cenv (_v: Val) attrs =
 
     // strip the MethodImpl pseudo-custom attribute
     // The following method implementation flags are used here
-    // 0x80 - hasPreserveSigImplFlag
-    // 0x20 - synchronize
+    // 0x0008 - no inlining
+    // 0x0020 - synchronize
+    // 0x0080 - preserve sig
+    // 0x0100 - aggressive inlining
+    // 0x2000 - async (runtime-async support, .NET 10+)
     // (See ECMA 335, Partition II, section 23.1.11 - Flags for methods [MethodImplAttributes])
     let attrs =
         attrs
@@ -9014,7 +9017,8 @@ and ComputeMethodImplAttribs cenv (_v: Val) attrs =
     let hasSynchronizedImplFlag = (implflags &&& 0x20) <> 0x0
     let hasNoInliningImplFlag = (implflags &&& 0x08) <> 0x0
     let hasAggressiveInliningImplFlag = (implflags &&& 0x0100) <> 0x0
-    hasPreserveSigImplFlag, hasSynchronizedImplFlag, hasNoInliningImplFlag, hasAggressiveInliningImplFlag, attrs
+    let hasAsyncImplFlag = (implflags &&& 0x2000) <> 0x0
+    hasPreserveSigImplFlag, hasSynchronizedImplFlag, hasNoInliningImplFlag, hasAggressiveInliningImplFlag, hasAsyncImplFlag, attrs
 
 and GenMethodForBinding
     cenv
@@ -9197,7 +9201,7 @@ and GenMethodForBinding
         | _ -> [], None
 
     // check if the hasPreserveSigNamedArg and hasSynchronizedImplFlag implementation flags have been specified
-    let hasPreserveSigImplFlag, hasSynchronizedImplFlag, hasNoInliningFlag, hasAggressiveInliningImplFlag, attrs =
+    let hasPreserveSigImplFlag, hasSynchronizedImplFlag, hasNoInliningFlag, hasAggressiveInliningImplFlag, hasAsyncImplFlag, attrs =
         ComputeMethodImplAttribs cenv v attrs
 
     let securityAttributes, attrs =
@@ -9474,6 +9478,7 @@ and GenMethodForBinding
                 .WithSynchronized(hasSynchronizedImplFlag)
                 .WithNoInlining(hasNoInliningFlag)
                 .WithAggressiveInlining(hasAggressiveInliningImplFlag)
+                .WithAsync(hasAsyncImplFlag)
                 .With(isEntryPoint = isExplicitEntryPoint, securityDecls = secDecls)
 
         let mdef =
@@ -10546,7 +10551,7 @@ and GenAbstractBinding cenv eenv tref (vref: ValRef) =
     let memberInfo = Option.get vref.MemberInfo
     let attribs = vref.Attribs
 
-    let hasPreserveSigImplFlag, hasSynchronizedImplFlag, hasNoInliningFlag, hasAggressiveInliningImplFlag, attribs =
+    let hasPreserveSigImplFlag, hasSynchronizedImplFlag, hasNoInliningFlag, hasAggressiveInliningImplFlag, hasAsyncImplFlag, attribs =
         ComputeMethodImplAttribs cenv vref.Deref attribs
 
     if memberInfo.MemberFlags.IsDispatchSlot && not memberInfo.IsImplemented then
@@ -10602,6 +10607,7 @@ and GenAbstractBinding cenv eenv tref (vref: ValRef) =
                 .WithSynchronized(hasSynchronizedImplFlag)
                 .WithNoInlining(hasNoInliningFlag)
                 .WithAggressiveInlining(hasAggressiveInliningImplFlag)
+                .WithAsync(hasAsyncImplFlag)
 
         match memberInfo.MemberFlags.MemberKind with
         | SynMemberKind.ClassConstructor
diff --git a/tests/FSharp.Compiler.ComponentTests/Conformance/AsyncHelpers.fs b/tests/FSharp.Compiler.ComponentTests/Conformance/AsyncHelpers.fs
new file mode 100644
index 00000000000..48191ce1160
--- /dev/null
+++ b/tests/FSharp.Compiler.ComponentTests/Conformance/AsyncHelpers.fs
@@ -0,0 +1,87 @@
+// Copyright (c) Microsoft Corporation.  All Rights Reserved.  See License.txt in the project root for license information.
+
+namespace FSharp.Compiler.ComponentTests.Conformance
+
+open Xunit
+open FSharp.Test.Compiler
+
+module AsyncHelpersTests =
+    
+    // This test verifies that F# can compile code that uses AsyncHelpers
+    // when targeting .NET 10+ (when AsyncHelpers becomes available)
+    [<Fact>]
+    let ``Code using AsyncHelpers should compile with appropriate warnings`` () =
+        let code = """
+module TestModule
+
+open System
+open System.Runtime.CompilerServices
+open System.Threading.Tasks
+
+#nowarn "57"
+
+type CEBuilder() =
+    member inline _.Return(x: 'T) : Task<'T> = Task.FromResult(x)
+    
+    member inline _.Bind(t: Task<'T>, [<InlineIfLambda>] f: 'T -> Task<'U>) : Task<'U> =
+        AsyncHelpers.Await t
+        |> f
+        
+    member inline _.Bind(t: Task, [<InlineIfLambda>] f: unit -> Task<'U>) : Task<'U> =
+        AsyncHelpers.Await t
+        |> f
+        
+    member inline _.Delay([<InlineIfLambda>]f: unit -> Task<'T>) : Task<'T> = f()
+    
+    [<System.Runtime.CompilerServices.MethodImplAttribute(0x2000s)>]
+    member inline _.Run(f: Task<'T>) : Task<'T> = f
+
+let ce = CEBuilder()
+
+let test() =
+    ce {
+        do! Task.Delay 100
+        return 42
+    }
+
+[<EntryPoint>]
+let main _ = 0
+"""
+        // This test documents that the code structure is valid F# syntax
+        // The actual AsyncHelpers.Await calls will only work when targeting .NET 10+
+        // For now, we expect a compilation error about AsyncHelpers not being defined
+        FSharp
+        |> withLangVersionPreview
+        |> asExe
+        |> withCode code
+        |> typecheck
+        |> shouldFail
+        |> ignore
+        
+    [<Fact>]
+    let ``InlineIfLambda attribute should be recognized`` () =
+        let code = """
+module TestModule
+
+open System.Runtime.CompilerServices
+
+type Builder() =
+    member inline _.Bind(x: int, [<InlineIfLambda>] f: int -> int) : int =
+        f x
+    
+    member inline _.Return(x: int) : int = x
+
+let builder = Builder()
+
+let test() =
+    builder {
+        let! x = 42
+        return x
+    }
+"""
+        FSharp
+        |> withLangVersionPreview  
+        |> asExe
+        |> withCode code
+        |> compile
+        |> shouldSucceed
diff --git a/tests/FSharp.Compiler.ComponentTests/EmittedIL/MethodImplAttribute/MethodImplAttribute.Async.fs b/tests/FSharp.Compiler.ComponentTests/EmittedIL/MethodImplAttribute/MethodImplAttribute.Async.fs
new file mode 100644
index 00000000000..7bfa0c4c3fc
--- /dev/null
+++ b/tests/FSharp.Compiler.ComponentTests/EmittedIL/MethodImplAttribute/MethodImplAttribute.Async.fs
@@ -0,0 +1,6 @@
+// Test for MethodImplOptions.Async (0x2000) - Runtime-Async support (.NET 10+)
+module M
+open System.Threading.Tasks
+
+[<System.Runtime.CompilerServices.MethodImplAttribute(0x2000s)>]
+let asyncMethod () : Task<int> = Task.FromResult(42)
diff --git a/tests/FSharp.Compiler.ComponentTests/EmittedIL/MethodImplAttribute/MethodImplAttribute.AsyncWithTask.fs b/tests/FSharp.Compiler.ComponentTests/EmittedIL/MethodImplAttribute/MethodImplAttribute.AsyncWithTask.fs
new file mode 100644
index 00000000000..4b364414bef
--- /dev/null
+++ b/tests/FSharp.Compiler.ComponentTests/EmittedIL/MethodImplAttribute/MethodImplAttribute.AsyncWithTask.fs
@@ -0,0 +1,12 @@
+// Test for MethodImplOptions.Async with Task return type
+module AsyncTaskTest
+open System.Threading.Tasks
+
+type TestClass() =
+    [<System.Runtime.CompilerServices.MethodImplAttribute(0x2000s)>]
+    member _.AsyncInstanceMethod() : Task<string> = 
+        Task.FromResult("hello")
+    
+    [<System.Runtime.CompilerServices.MethodImplAttribute(0x2000s)>]
+    static member AsyncStaticMethod() : Task<int> = 
+        Task.FromResult(100)
diff --git a/tests/FSharp.Compiler.ComponentTests/EmittedIL/MethodImplAttribute/MethodImplAttribute.fs b/tests/FSharp.Compiler.ComponentTests/EmittedIL/MethodImplAttribute/MethodImplAttribute.fs
index a13fee6baaf..f55ef16bb3c 100644
--- a/tests/FSharp.Compiler.ComponentTests/EmittedIL/MethodImplAttribute/MethodImplAttribute.fs
+++ b/tests/FSharp.Compiler.ComponentTests/EmittedIL/MethodImplAttribute/MethodImplAttribute.fs
@@ -77,3 +77,15 @@ module MethodImplAttribute =
     let ``Unmanaged_fs`` compilation =
         compilation
         |> verifyCompilation
+
+    // SOURCE=MethodImplAttribute.Async.fs         SCFLAGS="-a -g --optimize-" COMPILE_ONLY=1 POSTCMD="..\\CompareIL.cmd MethodImplAttribute.Async.dll"	# MethodImplAttribute.Async.fs - .NET 10 Runtime-Async
+    [<Theory; Directory(__SOURCE_DIRECTORY__, Includes=[|"MethodImplAttribute.Async.fs"|])>]
+    let ``Async_fs`` compilation =
+        compilation
+        |> verifyCompilation
+
+    // SOURCE=MethodImplAttribute.AsyncWithTask.fs         SCFLAGS="-a -g --optimize-" COMPILE_ONLY=1 POSTCMD="..\\CompareIL.cmd MethodImplAttribute.AsyncWithTask.dll"	# MethodImplAttribute.AsyncWithTask.fs - .NET 10 Runtime-Async with Task
+    [<Theory; Directory(__SOURCE_DIRECTORY__, Includes=[|"MethodImplAttribute.AsyncWithTask.fs"|])>]
+    let ``AsyncWithTask_fs`` compilation =
+        compilation
+        |> verifyCompilation
diff --git a/tests/FSharp.Test.Utilities/TestFramework.fs b/tests/FSharp.Test.Utilities/TestFramework.fs
index f7ec7f48001..d0de94ad896 100644
--- a/tests/FSharp.Test.Utilities/TestFramework.fs
+++ b/tests/FSharp.Test.Utilities/TestFramework.fs
@@ -315,7 +315,7 @@ let config configurationName envVars =
     let repoRoot = SCRIPT_ROOT ++ ".." ++ ".."
     let artifactsPath = repoRoot ++ "artifacts"
     let artifactsBinPath = artifactsPath ++ "bin"
-    let coreClrRuntimePackageVersion = "5.0.0-preview.7.20364.11"
+    let coreClrRuntimePackageVersion = "10.0.0"
     let csc_flags = "/nologo"
     let vbc_flags = "/nologo"
     let fsc_flags = "-r:System.Core.dll --nowarn:20 --define:COMPILED --preferreduilang:en-US"