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AxoWise User Guide

Overview

AxoWise is designed to help you develop contextual biological insights using protein interaction data, functional relationships, and literature-based knowledge extraction. It leverages multiple interconnected networks and advanced AI-driven techniques to provide meaningful insights.

Networks in AxoWise

AxoWise integrates three key networks:

  • Protein Network: Identifies and clusters protein communities based on interaction data, helping uncover functional modules.
  • Function Network: Maps functional relationships between proteins to explore biological roles and interactions.
  • Publication Network: Extracts relevant abstracts and knowledge from literature, linking biological concepts with scientific publications.

Graph Retrieval Augmented Generation (GRAG)

AxoWise employs Graph Retrieval Augmented Generation (GRAG) to enhance biological insight extraction:

  • Graph Retrieval: Retrieves structured biological knowledge from the integrated networks, ensuring context-aware data exploration.
  • Augmented Generation: Uses AI-powered summarization and text generation to provide actionable insights, integrating findings from the protein, function, and publication networks into a cohesive narrative. AxoWise is designed to help you develop contextual biological insights using protein interaction data, functional relationships, and literature-based knowledge extraction.

Quick Start

To get started with AxoWise quickly, follow the Quick Start Guide.

Detailed Topics

  1. Input Data → Learn about supported input formats.
  2. Protein Network → Detecting and clustering protein communities.
  3. Function Network → Exploring functional relationships between proteins.
  4. Publication Network → Extracting knowledge from literature.
  5. AI Extraction → AI-supported extraction of actionable insights.
  6. Troubleshooting → Common issues and solutions.

For a full explanation of how AxoWise works, refer to the sections above.