Open source bioinformatics and software infrastructure for science and beyond
Lepista Bioinformatics Lab is a virtual open-source laboratory publishing free tools for bioinformatics and general software development. Our projects range from sequence analysis pipelines and phylogenetic placers to modern API gateways and knowledge graph builders — all designed with quality architecture in mind.
We believe that good software and good science are inseparable. That's why every project here follows solid engineering principles: clean architecture, performance-first design, and clear documentation.
| Project | Description | Stack |
|---|---|---|
| mycelium | Secure, flexible, multi-tenant API Gateway |  |
| mycelium-webapp | Web dashboard for Mycelium |  |
| mycelium-http-tools-py | Python client for Mycelium HTTP tools |  |
| Project | Description | Stack |
|---|---|---|
| blutils | High-performance BLAST wrapper with consensus identity | |
| blutils-ui | Visual explorer for Blutils results | |
| classeq2 | Alignment-free phylogenetic placer based on k-mer composition | |
| tax2graph | Parse Catalog of Life taxonomy into a Neo4j graph database | |
| gene-connector-cli | CLI for gene analysis workflows | |
| Project | Description | Stack |
|---|---|---|
| noosphere-kg | Build knowledge graphs from unstructured text using LLMs | |
| agents-room | Collaborative environment for building and orchestrating AI agents | |
| Project | Description | Stack |
|---|---|---|
| clean-base | Clean architecture base utilities for Rust projects | |
| clean-base-py | Clean architecture base utilities for Python projects | |
We're looking for contributors who are passionate about bioinformatics, open science, or robust software engineering.
Whether you're a biologist who codes, a software engineer curious about life sciences, or just someone who wants to build cool things — you're welcome here.
Here's how you can get involved:
- Report issues — found a bug or have a suggestion? Open an issue in the relevant repository
- Submit pull requests — improvements, fixes, and new features are always welcome
- Improve documentation — clear docs are as valuable as good code
- Start a discussion — have an idea for a new tool or a collaboration? Let's talk
Check our repositories at github.com/LepistaBioinformatics and look for issues tagged good first issue or help wanted to get started.
Curious about why a mushroom genus became the symbol of a bioinformatics lab? Read the story behind the name:
- The Story Behind the Name — English
- A História Por Trás do Nome — Português (Brasil)
Science grows when knowledge is shared freely.