Annotated Bibliography

Publications

1. Corsi D, Ferrari M, Sastry A, McHugh W, Ling W, Sathish T, et al. A Hidden Risk Signal During Dofetilide Initiation: Early Sub-Threshold QTc Changes Predict Adverse Events. Heart Rhythm 2026 (in press). doi: 10.1016/j.hrthm.2026.03.194
2. Navara R, Kheiri B, McHugh W, Ferrari M, Corsi D, Sen A, Sinha A, Pavez G, Tseng Z, Gerstenfeld E. Clinical Performance of Novel Machine-Learning Based Antiarrhythmic Dosing Software: A Prospective Study. JACC 2025; 85(12 Suppl): 149. doi: 10.1016/S0735-1097(25)00634-5
3. Patel K, McHugh W, Paudel B, Sinha A, deLeon R, Asfaha D, Raj K, Higgins J, Talupula R, Pallod A, Rathore A, Okoroanyanwu S, Navara R. Machine Learning Algorithm for QTc Measurement and AAD Dosing Recommendations in Long QT mECG Dataset. Heart Rhythm 2024; 21(9):S786. doi: 10.1016/j.hrthm.2024.07.064
4. Navara R, McHugh W, Pallod A, Raj K, Sinha A, Deshpande M, Wang Y, De S, deLeon R, Bolaji O, Asfaha D, Okoroanyanwu S, Paudel B, Manohar R, Patel K. Usability of novel beat-by-beat ECG annotation software portal for generating large-scale machine learning training datasets. Europace 2024; 26(Suppl 1): euae102.580. doi: 10.1093/europace/euae102.580
5. Carlton EF, McHugh WM, McDonough K, Sturza J, Desch K, Cornell TT. Markers of Endothelial Dysfunction and Cytokines in High-Risk Pediatric Patients with Severe Sepsis. Am J Respir Crit Care Med 2020; 201(3): 380-384. doi: 10.1164/rccm.201904-0910LE
6. Beshish AG, Bradley JD, McDonough KL, Halligan NLN, McHugh WM, Sturza J, Hall MW, Cornell TT, Dahmer MK. The functional Immune Response of Patients on Extracorporeal Life Support. ASAIO J 2019; 65(1): 77-83. doi: 10.1097/MAT.0000000000000748
7. Sun L, Pham TT, Cornell TT, McDonough KL, McHugh WM, Blatt NB, Dahmer MK, Shanley TP. Myeloid-specific Gene Deletion of Protein Phosphatase 2A Magnifies MyD88- and TRIF-Dependent Inflammation following Endotoxin Challenge. J Immunol 2017; 198(1): 404-416. doi: 10.4049/jimmunol.1600221
8. Song Y, Chen P, Chung MT, Nidetz R, Park Y, Liu Z, McHugh WM, Cornell TT, Fu J, Kurabayashi K. AC Electroosmosis-enhanced Nanoplasmofluidic Detection of Ultralow-concentration Cytokine. Nano Lett 2017; 17(4): 2374-80. doi: 10.1021/acs.nanolett.6b05313
9. McHugh WM, Russell WW, Fleszar AJ, Rodenhouse PE, Rietberg SP, Sun L, Shanley TP, Cornell TT. Protein Phosphatase 2A activation attenuates inflammation in murine models of acute lung injury. Am J Physiol Lung Cell Mol Physiol 2016; 311(5): L903-L912. doi: 10.1152/ajplung.00007.2016
10. Oh BR, Chen P, Nidetz R, McHugh WM, Fu J, Shanley TP, Cornell TT, Kurabayashi K. Multiplexed Nanoplasmonic Temporal Profiling of T-cell Response under Immunomodulatory Agent Exposure. ACS Sens 2016; 1(7): 941-48. doi: 10.1021/acssensors.6b00240
11. Yu ZT, Guan H, Cheung MK, McHugh WM, Cornell TT, Shanley TP, Kurabayashi K, Fu J. Rapid, Automated, parallel quantitative immunoassays using highly integrated microfluidics and AlphaLISA. Sci Rep 2015; 5: 11339. doi: 10.1038/srep11339
12. Chen P, Chung MT, McHugh WM, Nidetz R, Li Y, Fu J, Cornell TT, Shanley TP, Kurabayashi K. Multiplex serum cytokine immunoassay using nanoplasmonic biosensor microarrays. ACS Nano 2015; 9(4): 4173-81. doi: 10.1021/acsnano.5b00396
13. Chang HN, Leroueil PR, Selwa K, Gasper CJ, Tsuchida RE, Wang JJ, McHugh WM, Cornell TT, Baker JR Jr, Goonewardena SN. Profiling inflammatory responses with microfluidic immunoblotting. PLoS One 2013; 8(11): e81889. doi: 10.1371/journal.pone.0081889
14. Cornell TT, Fleszar A, McHugh WM, Blatt NM, LeVine AM, Shanley TP. Mitogen-activated Protein Kinase Phosphatase 2, MKP-2, Regulates Early Inflammation in Acute Lung Injury. Am J Physiol Lung Cell Mol Physiol 2012; 303(3):L251-8. doi:10.1152/ajplung.00063.2012

Extramural Invited Presentations

1. “Increasing PP2A activity decreases chemokine production and attenuates inflammation in acute lung injury.” Oral Platform Presentation at the Pediatric Academic Societies 2010 Annual Meeting; Vancouver, British Columbia. May 1-4, 2010.
2. “Personalized Immunomodulation in High-risk Sepsis Patients in a Pediatric Critical Care Unit.” Society of Critical Care Medicine 46th Critical Care Congress; Honolulu, Hawaii. Jan 21-25, 2017.
3. “Multiplex, Temporal Immunophenotyping with Microfluidic-based Localized Surface Plasmon Resonance.” Society of Critical Care Medicine 46th Critical Care Congress; Honolulu, Hawaii. Jan 21-25, 2017.